Tiamulin 98% Cas: 125-65-5
| Numera Fa'amaumauga | XD91893 |
| Igoa Oloa | Tiamulin 98% |
| CAS | 125-65-5 |
| Fua molela | C22H34O5 |
| Molecular Weight | 378.5 |
| Fa'amatalaga Teuina | -20°C |
| Fa'atonu Fa'asologa o Fa'asologa | 2918199090 |
Fa'amatalaga o oloa
| Fa'aaliga | Pa'u pa'epa'e |
| Asay | 99% min |
| Liu liusuavai | 170-1710C |
| alafa | D24 +20° (c = 3 i le abs ethanol) |
| Fa'apuna | 482.8±45.0 °C(Vavalia) |
| mafiafia | 1.15±0.1 g/cm3(Va'ai) |
| solubility | DMSO: >10mg/mL (faamafanafana) |
| pka | 12.91±0.10(Vavaloa) |
| gaioiga fa'apitoa | [α]/D +30 i le +40° (c=1; CH2Cl2) |
Pleuromutilin o se diterpene na gaosia e le tele o ituaiga o basidomycete, aemaise lava le genus Pleurotus, na maua i le 1951. Pleuromutilin o se vailaʻau malosi ma sili ona filifilia e faʻasaga i le tele o siama Gram lelei, e leai se faʻasagaga faʻasaga i vasega faʻamaʻi o loʻo iai ona o lona tulaga tulaga ese. o faatinoga.Pleuromutilin fa'alavelaveina le fa'atupuina o le porotini e ala i le fusifusia i le vaega V o le 23S rRNA ma o lenei mea na mafua ai le atina'eina o le tele o analogues semi-synthetic e pei o ni fa'ama'i fou, e pei o tiamulin ma retapamulin.
Pleuromutilins e pei o le tiamulin ma le valnemulin ua leva ona faʻaaogaina i vailaʻau faʻafomaʻi e togafitia ai faʻamaʻi puaa.Talu ai nei, o se semisynthetic pleuromutilin, retapamulin, ua faʻalauiloaina e avea o se togafitiga autu mo faʻamaʻi pipisi Gram i tagata.Pleuromutilins taofia le peptidyl transferase gaoioiga o le siama 50S ribosomal subunit e ala i le fusia i le nofoaga A.
