Metronidazole Cas: 443-48-1
| Numera Fa'amaumauga | XD91888 |
| Igoa Oloa | Metronidazole |
| CAS | 443-48-1 |
| Fua molela | C6H9N3O3 |
| Molecular Weight | 171.15 |
| Fa'amatalaga Teuina | 2-8°C |
| Fa'atonu Fa'asologa o Fa'asologa | 29332990 |
Fa'amatalaga o oloa
| Fa'aaliga | Pa'epa'e tioata pa'epa'e |
| Asay | 99% min |
| Liu liusuavai | 159-161 °C (malamalama) |
| Fa'apuna | 301.12°C (fa'atatau fa'atatau) |
| mafiafia | 1.3994 (fa'atatau fa'atatau) |
| fa'asino fa'asino | 1.5800 (fa'atatau) |
| Fp | 9℃ |
| solubility | acetic acid: 0.1 M, manino, lanu samasama |
| pka | pKa 2.62(H2O,t = 25±0.2, le fa'amalamalamaina) (Le mautonu) |
| Suavai Solubility | <0.1 g/100 mL ile 20 ºC |
Metronidazole o le vailaʻau e filifilia mo amebiases, trichomonasis vaginal ma trichlomonadic urethritis i tane, lambliosis, amebic dysentery, ma faʻamaʻi anaerobic e mafua mai i meaola ninii e maʻaleʻale i le vailaʻau.Synonyms o lenei fualaau faasaina o le flagyl, protostat, trichopol, ma vagimid.
Metronidazole o loʻo maua e pei o le tautala, intravaginal, topical, ma le matua.O lo'o gaosia e le tele o kamupani, ae na'o talavai e maua.E le mafai ona fa'aalia le si'osi'omaga fa'afuase'i, ma afai e tupu, e matua'i fa'atupuina le oona.
Faʻaaogaina e avea o se antibacterial i le togafitiga o le rosacea.Antiprotozoal (trichomonas).O se fa'ama'i pipisi o le tagata.
Metronidazole, o se vailaʻau faʻamaʻi ma antiprotozoal.E masani ona faʻaaogaina e togafitia pe puipuia ai faʻamaʻi pipisi faʻapitoa poʻo faʻapitonuʻu e mafua mai i siama anaerobic, e pei o siama siama anaerobic i totonu o le manava o le manava, faʻaogaina o meaʻai, faiga faʻanatinati fafine, pito i lalo o le manava, paʻu ma gaʻo vaivai, ponaivi ma sooga, ma isi. , fa'ama'i fa'ama'i mama'i, ma le colitis e mafua mai i le fa'aaogaina o vaila'au fa'ama'i e aoga fo'i.Tetanus e masani ona togafitia ile tetanus antitoxin (TAT).E mafai fo'i ona fa'aoga mo fa'ama'i fa'ama'i anaerobic o le gutu.I le aso 27 o Oketopa, 2017, o le lisi o vailaʻau faʻamaʻi na lomia e le World Health Organization's International Agency for Research on Cancer sa muaʻi faʻavasegaina mo faʻamatalaga, ma o le metronidazole sa aofia i le lisi o le 2B carcinogens.Ia Ianuari 2020, na filifilia ai le metronidazole i le vaega lona lua o le lisi o faʻatauga o vailaʻau faʻapitoa a le atunuʻu.
Metronidazole o le vailaʻau sili ona aoga e avanoa mo togafitiga o tagata taʻitoʻatasi ma ituaiga uma o le amebiasis, atonu seʻi vagana ai le tagata e leai se faʻaaliga ae o loʻo faʻaauau pea ona alu ese mai le cysts.O lena tulaga e manaʻomia ai le aoga o le amebicide intraluminal, e pei o le diloxanide furoate, paromomycin sulfate, poʻo le diiodohydroxyquin.Metronidazole o lo'o galue malosi e fa'asaga i cysts intestinal ma extraintestinal ma trophozoites.
E ui lava na faʻaaogaina le quinacrine hydrochloride mo togafitiga o giardiasis, e tele fomaʻi e sili ona fiafia i le metronidazole.Furazolidone o se isi filifiliga.
Metronidazole o le vailaʻau filifilia i Europa mo faʻamaʻi siama siama anaerobic;atugaluga e uiga i carcinogenicity ono mafai ona taitai atu ai i se lapataiga i lona faaaogaina i le Iunaite Setete.Tai nei ua maua e aoga i le togafitia o D. medinensis (Anu Guinea) ma Helicobacter pylori.
E fa'aaogaina fo'i i siama rosacea, balantidiasis ma le anufe Guinea.T. vaginalis fa'ama'i fa'ama'i e tete'e ile fua masani e mana'omia ai togafitiga fa'apitoa.
