O se monoclonal antibody (mAb 8281) faapitoa mo le terminal β-galactose (βGal) o glycosphingolipids (GSL) ma glycoproteins na gaosia mai isumu tui puipuia i le lipid extract mai sela fou o le lymphocytic leukemia (ALL).Immuno-thin layer chromatography (ITLC) ma faʻataʻitaʻiga tauvaga faʻatasi ai ma tulaga faʻamama faʻaituau GSL, sugars free, ma neoglycoproteins synthetic na faʻaalia ai le mAb 8281 e malosi faʻatasi ma LacCer, GalCer ma Gal-β-O-(CH3)2S(CH3)2- CONH-(Gal-β-O-CETE) e fesoʻotaʻi ma le albumin serum bovine (BSA).O le suka penultimate sa iai foi sona sao i le fusifusia.O le antibody e le'i fa'agaoioi ma ga'o ga'o fa'atasi ma fausaga αGal fa'amau ma vaega fa'amau e le'i feso'ota'i.Ole tui ole immunoperoxidase ma le tafe o le cytometry ma le mAb 8281 na faʻaalia ai le pisia lelei i luga ole tele o masini, e aofia ai maso lamolemole, mucosa gastrointestinal, lymph node B sela ma monocytes.ITLC suʻesuʻega o le GSL tuʻufaʻatasiga o neoplasms fou B cell e faʻaaoga ai mAb 8281 faʻamaonia le i ai o le lactosylceramide ma galactosylceramide i neoplasms o tulaga eseese o le eseesega.Ona o lona faʻapitoa mo toega gaʻo gaʻo βGal, mAb 8281 atonu e aoga i suʻesuʻega faʻatulagaina ma galuega ole GSL.
