Oloa

Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride ose vailaʻau faʻapipiʻi ma faʻaoga talafeagai i le matata o vailaʻau ma suʻesuʻega vailaʻau.E aofia ai se vaega o le benzyl o loʻo faʻapipiʻi i se gaioiga o le carbamate, lea e fesoʻotaʻi atu i le hexahydro-1H-pyrrolizin-7a-ylmethyl moiety.O le faʻaopoopoga o le hydrochloride i le faʻapipiʻi e faʻaalia ai le i ai o se chloride ion, lea e faʻaleleia ai lona solubility i le vai. O lenei faʻapipiʻi atonu e tele faʻaoga ona o ona foliga faʻavae.Carbamates, i se tulaga lautele, ua lauiloa e faʻaalia ai gaioiga faʻapitoa, e aofia ai faʻamaʻi faʻamaʻi, faʻamaʻi kanesa, ma mea faʻamalosi.O le i ai o le vaega o le benzyl i le benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride e mafai ona maua ai le lipophilicity faʻaleleia atili, e mafai ai ona faigofie ona sopoia membranes cellular.E mafai ona aoga lenei mea mo le tuʻuina atu o vailaʻau ma le faʻaleleia atili o le bioavailability.Hexahydro-1H-pyrrolizin-7a-ylmethyl moiety, lea e taʻua foi o le piperidinyl moiety, e masani ona maua i mea faʻapitoa.Piperidines ua lauiloa mo la latou matafaioi o le iniseti enzyme, neurotransmitter modulators, ma le anti-inflammatory agents.O le tu'ufa'atasia o lenei vaega i totonu o le fa'aputuga e mafai ona fa'aleleia atili ai ana gaioioiga olaola ma le malosi fa'apitoa.Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride e mafai ona su'esu'eina e fai ma sui o fualaau fa'asaina mo tulaga e pei ole epilepsy, kanesa, toto maualuga, po'o ma'i neurodegenerative.E mafai foi ona faʻaaogaina e avea o se poloka fale poʻo se vaeluaga i le tuʻufaʻatasia o isi mea faʻaolaola. e tatau ona faia.O le a fesoasoani lea e fuafua ai le saogalemu, aoga, ma le sa'o o le fa'aogaina o le benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride, ma iu ai ina o'o atu i lona fa'aogaina i le falema'i.