itulau_fanua

Oloa

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-tasi Cas:1044871-04-6

Fa'amatalaga Puupuu:

Numera fa'amaumauga: XD90961
Cas: 1044871-04-6
Fuafua mole: C24H29N3O4
Molecular Weight: 423.5
Avanoa: E tele
Tau:  
mua'i afifi:  
Vaega Tele: Talosaga Sesii

 


Fa'amatalaga Oloa

Faailoga o oloa

Numera Fa'amaumauga XD90961
Igoa Oloa 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-tasi

CAS

1044871-04-6

Fuafua mole

C24H29N3O4

Molecular Weight

423.5
Fa'amatalaga Teuina  
Fa'atonu Fa'asologa o Fa'asologa  

 

Fa'amatalaga o oloa

Fa'aaliga  
Su'ega  
Bmea fa'asu'u 612.6±65.0 °C(Vailoaina)
Malosi 1.25±0.1 g/cm3(Va'ai)
Acidity coefficient (pKa)9.54±0.20(Vailoaina)

 

O le RVX-297 o se mea e sili ona malosi, tautala fa'amalosi BET inhibitor filifilia mo BD2.O le IC50s o le RVX-297 mo BRD2(BD2), BRD3(BD2), ma le BRD4(BD2) e 0.08, 0.05, ma le 0.02 μM.O le RVX-297 e taofia le faʻaalia o le tele o genes inflammatory cell immune.Le aoga o le RVX-297 i faʻataʻitaʻiga faʻataʻitaʻiga o le afaina tele ma le autoimmunity.


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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-tasi Cas:1044871-04-6