2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-tasi Cas:1044871-04-6
Numera Fa'amaumauga | XD90961 |
Igoa Oloa | 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-tasi |
CAS | 1044871-04-6 |
Fuafua mole | C24H29N3O4 |
Molecular Weight | 423.5 |
Fa'amatalaga Teuina | |
Fa'atonu Fa'asologa o Fa'asologa |
Fa'amatalaga o oloa
Fa'aaliga | |
Su'ega | |
Bmea fa'asu'u | 612.6±65.0 °C(Vailoaina) |
Malosi | 1.25±0.1 g/cm3(Va'ai) |
Acidity coefficient | (pKa)9.54±0.20(Vailoaina) |
O le RVX-297 o se mea e sili ona malosi, tautala fa'amalosi BET inhibitor filifilia mo BD2.O le IC50s o le RVX-297 mo BRD2(BD2), BRD3(BD2), ma le BRD4(BD2) e 0.08, 0.05, ma le 0.02 μM.O le RVX-297 e taofia le faʻaalia o le tele o genes inflammatory cell immune.Le aoga o le RVX-297 i faʻataʻitaʻiga faʻataʻitaʻiga o le afaina tele ma le autoimmunity.
Tapuni