Oloa

1-Methyl-4-pyrazole boronic acid pinacol ester o se vailaʻau faʻamaʻi e faia se sao taua i le fanua o kemisi oona ma suʻesuʻega vailaʻau.O loʻo i ai se vaega o le boronic acid, lea e avea ai ma poloka fale taua mo le faʻapipiʻiina o molelaʻau faʻaola eseese. O se tasi o faʻaoga muamua o le 1-Methyl-4-pyrazole boronic acid pinacol ester o loʻo i totonu o le fanua o vailaʻau kemisi.E masani ona faʻaaogaina e avea o se mea muamua poʻo se vaeluagalemu i le tuʻufaʻatasiga o vailaʻau vailaʻau.Boronic acids ua lauiloa mo lo latou gafatia e fausia ai faʻalavelave faʻamautu ma nisi enzymes, aemaise lava protease.O lenei meatotino e avea ai i latou ma mea faigaluega lelei mo le atinaʻeina o enzymes inhibitors e mafai ona faʻaogaina faʻamaʻi faʻapitoa.E ala i le tu'ufa'atasia o le vaega o le pyrazole i totonu o le boronic acid, o le fa'aputuga fa'atupuina e fa'aalia ai le fa'aleleia atili o feso'ota'iga ma le filifilia i le enzyme taula'i.O le mea lea ua avea ai le 1-Methyl-4-pyrazole boronic acid pinacol ester o se poloka fale taua mo taumafaiga su'esu'e fualaau o lo'o tulimata'i fa'ama'i fa'avae protease e pei o le kanesa, fulafula, ma fa'ama'i viral. E le gata i lea, o le boronic acid i le 1-Methyl-4-pyrazole boronic acid pinacol ester e mafai ona oʻo i faʻalavelave faʻamaʻi eseese, e pei o le Suzuki-Miyaura cross-coupling reaction ma le Heck reaction.O nei gaioiga e faʻatagaina ai le faʻavaeina o fusi carbon-carbon, faʻafaigofie le tuʻufaʻatasia o fausaga faʻapitoa lavelave.O le vaega o le pyrazole e faʻaopoopo atili ai le eseesega ma le faʻatinoga i mea faʻapipiʻi faʻapipiʻiina, ma avea ai le 1-Methyl-4-pyrazole boronic acid pinacol ester o se mea faʻapitoa i le faʻaogaina o meaola. atina'e o mea fa'avae boron.O le vaega o le boronic acid o loʻo i ai mea faʻapitoa e mafai ai ona auai i faiga faʻapipiʻi a le tagata lava ia, e taʻitaʻia ai le faʻavaeina o fausaga supramolecular.O lenei tomai ua suʻesuʻeina i le matata o mea faʻasaienisi e fatu ai mea aoga, e pei o gels, ata tifaga, ma nanoparticles, lea e mafai ona maua ai faʻaoga i mea tau eletise, catalysis, ma le tuʻuina atu o vailaʻau. I le aotelega, 1-Methyl-4-pyrazole boronic acid pinacol ester o se faʻalapotopotoga faʻapitoa ma le tele o faʻaoga.O lona fa'aogaina o le boronic acid e mafai ai ona tu'ufa'atasia mole mole lavelave, ma avea ai ma poloka faufale taua i le su'esu'eina o vaila'au ma le fa'aogaina o meaola.E le gata i lea, o ona uiga faʻapitoa e mafai ai ona faʻavaeina mea supramolecular ma faʻaoga faʻaoga i vaega eseese.I le aotelega, o lona natura faʻapitoa e faia ai le 1-Methyl-4-pyrazole boronic acid pinacol ester o se meafaigaluega taua mo tagata suʻesuʻe i aʻoaʻoga faʻasaienisi eseese.