Oloa

Trifluoroacetamide, faʻatasi ai ma le vailaʻau vailaʻau CF3CONH2, o se faʻapipiʻi e maua ai faʻaoga eseese i vaega eseese, e aofia ai vailaʻau, agrochemical, ma alamanuia faʻalapotopotoga.O vaega puipuia o kulupu fa'atino e fa'apipi'i mo sina taimi i atomi fa'apitoa i totonu o se mole e puipuia ai fa'alavelave e le mana'omia i le taimi o suiga fa'ama'i.Trifluoroacetamide galue o se vaega puipuia mo amines, aemaise amines muamua.E ala i le fa'atupuina o se amine muamua ma le trifluoroacetamide, e puipuia lelei ai fa'agaioiga e le mana'omia, fa'atagaina le fa'avasegaina o isi vaega fa'atino o lo'o iai i le mole.O lenei taʻiala e puipuia ai le puipuia o loʻo faʻaaogaina lautele i le tuʻufaʻatasia o vailaʻau faʻapitoa faʻamalositino, faʻamautinoaina o faʻamaʻi faʻamaʻi faʻapitoa e tupu naʻo nofoaga faʻapitoa.Vilsmeier-Haack reaction o se vailaʻau faʻaaogaina mo le tuʻufaʻatasia o mea faʻapitoa eseese, e aofia ai aldehydes manogi ma ketones.Trifluoroacetamide, faʻatasi ma le chloride acid ma le Lewis acid catalyst, e fausia ai le Vilsmeier-Haack reagent, lea e galue o se meafaigaluega tele mo le faʻaogaina o mea manogi.O lenei tali e faʻaaogaina lautele i le falemaʻi vailaʻau mo le tuʻufaʻatasia o vailaʻau faʻapitoa ma vailaʻau faʻamalosi (APIs).O le natura fa'agaoioiga o le tuufaatasiga e mafai ai ona fa'aofia vaega fa'apitoa e mana'omia mo gaioiga fa'ato'aga.Trifluoroacetamide-based molecules e mafai ona faʻaalia le faʻaleleia atili o vailaʻau faʻamaʻi poʻo vailaʻau faʻamaʻi faʻatusatusa i a latou analogs, faʻaleleia atili lo latou aoga i le puipuia o fualaʻau mai vao, faʻamaʻi, ma faʻamaʻi.Trifluoroacetamide derivatives ua faʻaalia le malosi o le gaioiga e faasaga i le lautele o fusi o meaola faʻatatau aʻo faʻaitiitia o latou aʻafiaga leaga i le siosiomaga.O loʻo aʻafia i le gaosiga o solvents, e pei o le N-methyl-N-(trifluoroacetyl)acetamide (MTAA), faʻaaogaina i faiga faʻapisinisi eseese.Trifluoroacetamide-o loʻo i ai solvents ei ai mea e manaʻomia, e aofia ai le maualuga o mea e faʻafefe ai, maualalo le mamafa o le ausa, ma le faʻamautuina o vailaʻau, e faʻaogaina ai mo faʻaoga e pei o le aveeseina, vavaeeseina, ma le faʻamamaina o mea faʻapipiʻi. aemaise i vaila'au ma vaila'au fa'ato'aga.E avea o se vaega puipuia mo amines, faʻatagaina suiga filifilia i le taimi faʻalavelave faʻapipiʻiina.Trifluoroacetamide-faʻavae faʻapipiʻi e maua le faʻaogaina e fai ma mea faʻapitoa i le gaosiga o vailaʻau, vailaʻau faʻamaʻi, ma vailaau faʻasaina, faʻaleleia atili le aoga ma le faʻaleleia o le siosiomaga.E le gata i lea, o le trifluoroacetamide o loʻo aʻafia i le gaosiga o solvents faʻapitoa e faʻaaogaina i faiga faʻapisinisi eseese.O le agavaʻa ma le faʻaogaina o le trifluoroacetamide e avea ai ma mea taua i le tele o alamanuia.