Oloa

Tert-butyl 3-acetylpyrazolo [1,5-a] pyridin-5-ylcarbamate o se vailaʻau vailaʻau e lauiloa mo ana faʻaoga eseese i le faʻaogaina o meaola ma vailaʻau kemisi.Faatasi ai ma lona fausaga mole mole tulaga ese, o lenei tuufaatasiga o loʻo i ai mea manaia ma faʻaoga faʻaoga i vaega eseese o suʻesuʻega. poloka i le fa'aogaina o meaola.O lona pyrazolo [1,5-a] pyridine scaffold, faʻatasi ma le carbamate ma le acetyl functional groups, e maua ai le avanoa e faʻapipiʻi ai lenei faʻapipiʻi i totonu o le tuʻufaʻatasiga o molelaʻau faʻapitoa lavelave.E mafai ona faʻaaogaina e fai ma mea amata mo le fausiaina o mea faʻapipiʻi heterocyclic, vailaʻau vailaʻau, poʻo isi vaega taua o meaola. ma le mauaina o fualaau faasaina.O le i ai o le pyrazolo [1,5-a] pyridine core o loʻo taʻu mai ai lona gafatia e avea o se pharmacophore, o se vaega faʻavae e nafa ma le gaioiga o meaola o se vailaʻau.E ala i le suia o mea e suitulaga i le carbamate poʻo vaega acetyl, e mafai ona suʻesuʻeina sootaga faʻavae-gaioiga ma faʻamalieina mea tau vailaʻau.O lenei tuufaatasiga e mafai ona faʻataʻitaʻiina e faasaga i sini faʻale-aganuʻu eseese, e pei o enzymes poʻo faʻafeiloaʻi, e iloa ai mea e mafai ona taʻitaʻia mo le atinaʻeina o vailaʻau fou. E le gata i lea, e mafai foi e tert-butyl 3-acetylpyrazolo [1,5-a] pyridin-5-ylcarbamate. avea o se meafaigaluega aoga i suʻesuʻega faʻaola kemisi, e mafai ai ona suʻesuʻeina faʻagasologa o meaola ma fegalegaleaiga mole.O lona fausaga tulaga ese, faʻatasi ma le avanoa e tuʻuina atu ai faʻailoga talafeagai poʻo vaega faʻatino, e mafai ona faʻafaigofieina le faʻailogaina ma le siakiina o meaola faʻapitoa, e pei o proteins poʻo nucleic acids, i suʻega feaveaʻi poʻo biochemical.O lenei tuufaatasiga e mafai ona fesoasoani i tagata suʻesuʻe e faʻamalamalamaina auala olaola, fegalegaleaiga protein-protein, poʻo le faiga o gaioiga o togafitiga faʻapitoa. aemaise i le atinaʻeina o mea aoga poʻo vali.E mafai ona fetuutuuna'i ona mea fa'aeletonika ma fa'ama'i e saofagā i le fa'atulagaina o mea e mana'omia ai mea fa'apitoa, eletise, po'o masini.Mo se faʻataʻitaʻiga, e mafai ona tuʻufaʻatasia i totonu o le faʻavae o semiconductors organic poʻo le faʻaaogaina o se chromophore i moli-emitting diodes poʻo le la o le la. fa'atasi ma le tele o fa'aoga i le tu'ufa'atasiga fa'aola, kemisi fa'afoma'i, biology kemikolo, ma mea fa'asaienisi.O lona fausaga tulaga ese ma vaega faʻatino e maua ai se faʻavae mo le tuʻufaʻatasia o mole lavelave, le atinaʻeina o vailaʻau fou, suʻesuʻega o gaioiga faʻasolosolo, ma le mamanu o mea aoga.O fa'aoga eseese o lenei fa'aputuga ua fa'ailoa mai ai lona taua i vaega eseese o su'esu'ega ma lona gafatia e saofagā i le alualu i luma i le faasaienisi ma tekinolosi.