Streptavidin mai Streptomyces avidinii CAS:9013-20-1
Numera Fa'amaumauga | XD90329 |
Igoa Oloa | Streptavidin mai Streptomyces avidinii |
CAS | 9013-20-1 |
Fuafua mole | C14H17BrClNO2S |
Molecular Weight | 378.71 |
Fa'amatalaga Teuina | -15 i le -20 °C |
Fa'atonu Fa'asologa o Fa'asologa | 35040090 |
Fa'amatalaga o oloa
Fa'aaliga | Pa'u pa'epa'e |
Su'ega | 99% |
Mo na'o su'esu'ega fa'aoga, ae le mo le fa'aogaina e tagata | fa'aoga su'esu'e, ae le mo le fa'aogaina e tagata |
Alkyne-hinged 3-fluorosialyl fluoride (DFSA) o loʻo i ai se vaega alkyne na faʻaalia o se faʻaogaina faʻavae faʻapitoa-faʻapitoa e le mafai ona toe faʻaogaina le inhibitors o sialidases.O le ester-protected analog DFSA (PDFSA) o se membrane-permeable precursor o le DFSA ua fuafuaina e faʻaoga i sela ola, ma na faʻaalia e fausia ai faʻaopoopoga faʻatasi ma siama, siama, ma sialidases tagata.O le fluorosialyl-enzyme addduct e mafai ona faʻapipiʻiina i se biotin faʻapipiʻi azide e ala i le kiliki tali ma iloa e le streptavidin-specific lipoti faailoilo.Ole chromatography sua-su'esu'e/su'esu'ega fa'ase'e i luga ole vaega ole peptide tryptic ua fa'ailoa mai ai ole vaega ole 3-fluorosialyl e suia ai toega tyrosine ole sialidases.O le DFSA na faʻaaogaina e faʻaalia ai faʻamaʻi pipisi ma le suʻesuʻeina o le faʻamaʻi pipisi i le vailaʻau faʻamaʻi oseltamivir acid, ae o le PDFSA na faʻaaogaina mo faʻataʻitaʻiga i totonu o suiga o gaioiga sialidase i sela ola.