Oloa

(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine o se chiral compound ma faʻaoga eseese i le fanua o vailaʻau. -N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine o loʻo i le atinaʻeina o le faʻaogaina o le serotonin reuptake inhibitors (SSRIs).SSRIs o se vasega o vailaʻau e masani ona faʻaaogaina e togafitia ai le atuatuvale, faʻalavelave popole, ma isi faʻafitauli o le soifua maloloina o le mafaufau.O lenei tuufaatasiga e galue o se mea muamua poʻo se mea amata i le tuʻufaʻatasiga o le serotonin reuptake inhibitors filifilia, faʻatagaina mo le atinaʻeina o enantiomers faʻapitoa ma faʻaleleia mea faʻapitoa.E ala i le tuʻufaʻatasia (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine i totonu o le fausaga o le vailaʻau, e mafai e tagata suʻesuʻe ona faʻavasegaina ana mea tau vailaʻau, e pei o lona vavalalata mo tagata faʻatau serotonin, e mafua ai le faʻaleleia atili o le aoga ma faʻaitiitia ai aʻafiaga. E le gata i lea, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine e mafai ona faʻaaogaina e avea o se poloka fale i le faʻapipiʻiina o isi bioactive fa'atasi.O lona natura chiral ma le tele o fausaga e avea ai ma mea aoga amata mo le fausiaina o molelaʻau lavelave.E mafai e tagata suʻesuʻe ona faʻaogaina nofoaga eseese i luga o le mole e faʻafeiloaʻi ai vaega eseese poʻo le suia o ana kemisi faʻataʻitaʻiga e fatu ai ni sui faʻatau fualaau fou. E le gata i lea, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine ua su'esu'eina mo lona fa'aaogaina e togafitia ai le ma'i o Parkinson.O suʻesuʻega ua faʻaalia ai o lenei mea faʻapipiʻi o loʻo faʻaalia ai le dopamine agonist, o lona uiga e mafai ona faʻaosofia le dopamine receptors, lea e masani ona aʻafia i le maʻi o Parkinson.E mafai ona i ai ni togafitiga faʻapitoa e faʻaitiitia ai faʻamaoniga e fesoʻotaʻi ma lenei maʻi neurodegenerative. fa'afefiloi, ma o lona fa'aaogaina e tatau ona taulimaina ma le fa'aeteete.Tagata suʻesuʻe ma faʻapolofesa o loʻo galulue faʻatasi ma lenei faʻalapotopotoga e manaʻomia le tausisia o taʻiala saogalemu ma taualumaga ina ia mautinoa le taulimaina lelei ma faʻaitiitia ai lamatiaga. I le aotelega, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl ) propanamine ose faʻapipiʻi taua i le atinaʻeina o le faʻaogaina o le serotonin reuptake inhibitors ma isi meaola olaola.O lona natura natura, fausaga faʻapitoa, ma gaioiga faʻapitoa e mafai ona avea ma poloka fale taua i suʻesuʻega vailaʻau.Faʻaauau suʻesuʻega ma suʻesuʻega o (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine e mafai ona saofagā i le atinaʻeina o vailaʻau fou ma togafitiga talafeagai mo faʻafitauli eseese.