Polystyrene sulfonic acid CAS:28210-41-5
Numera Fa'amaumauga | XD90753 |
Igoa Oloa | Polystyrene sulfonic acid |
CAS | 28210-41-5 |
Fuafua mole | C8H8O3S |
Molecular Weight | 184.212 |
Fa'amatalaga Teuina | Ambient |
Fa'amatalaga o oloa
Fa'aaliga | Suava mama |
Su'ega | 99% |
Hyperkalemia i le taimi ole renin-angiotensin-aldosterone system inhibition (RAAS-I) e mafai ona taofia le tuʻuina atu o mea sili ona lelei.O togafitiga e aofia ai resini e fusifusia ai le sodium polystyrene sulfonate potassium, ae o popolega o le saogalemu ma le aoga o loʻo iai, e aofia ai le colonic necrosis (CN).Na suʻesuʻeina isi sui, ae e leʻi faʻatatauina le tau-aoga. Matou te faia se suʻesuʻega tau-aoga o tagata mai fafo ≥ 18 tausaga le matua maua RAAS-I tumau, faʻatasi ai ma se talaʻaga o le hyperkalemia poʻo faʻamaʻi fatugaʻo tumau, faʻatonuina poʻo le sodium polystyrene sulfonate. po'o se fa'ata'ita'iga fa'aigoa "fuala'au X" resini fusifusia mo hyperkalemia tumau.Na maua faʻamaumauga mai tusitusiga o loʻo iai.Sa matou fa'aogaina se fa'ata'ita'iga au'ili'ili fa'ai'uga fa'atasi ma su'esu'ega ma'ale'ale a Monte Carlo, mai le va'aiga a le au totogi soifua maloloina ma le 12 masina.O tau na fuaina i tala Amerika.O le aoga na fuaina i le lelei-fetuuna'i-tausaga-tausaga (QALYs), ma faʻaopoopoga tau-effective ratios (ICERs). Fualaau X e le mafai ona sili atu nai lo le $ 10.77 i aso taʻitasi inumaga ina ia taugofie, i le naunau e totogi ( WTP) e $50,000/QALY.I le $40.00 ile fua ole aso, ole vaila'au X na maua le fa'aopoopoga ole tau ole tau ole $26,088,369.00 ile QALY maua.O le suʻesuʻega faʻapitoa e tasi-auala na faʻaalia ai le sodium polystyrene sulfonate e avea ma filifiliga taugofie mo faʻalavelave CN ≤ 19.9%.O tapula'a e aofia ai fa'amatalaga le atoatoa i taunu'uga o gasegase i fafo ma le leai o ni fa'amatalaga e fa'atusatusa sa'o ai le sodium polystyrene sulfonate i isi mea e ono mafai. O isi mea e ono le taugofie se'i vagana ua tutusa le tau ma le sodium polystyrene sulfonate.O lenei au'ili'iliga e mafai ona ta'ita'ia ai fa'ai'uga e fa'atatau i le fa'aaogaina o isi vaila'au mo le pulea o le hyperkalemia tumau, ma fa'ailoa mai e fa'aaoga le sodium polystyrene sulfonate e fai ma fa'atonuga i su'esu'ega fa'afoma'i a nei vaila'au.