Iodonitrotetrazolium chloride CAS:146-68-9
Numera Fa'amaumauga | XD90473 |
Igoa Oloa | Iodonitrotetrazolium chloride |
CAS | 146-68-9 |
Fuafua mole | C19H13ClIN5O2 |
Molecular Weight | 505.70 |
Fa'amatalaga Teuina | 2 i le 8 °C |
Fa'atonu Fa'asologa o Fa'asologa | 32129000 |
Fa'amatalaga o oloa
Fa'ailoaga | H-NMR |
Fa'aaliga | Samasama mumu e pa'u moli |
Su'ega | >99% |
Solubility | Fofo manino |
Interferon-induced transmembrane protein 1 (IFITM1) o se tasi o sui o le aiga o le transmembrane protein e fa'aosoina.I lenei suʻesuʻega, na matou lipotia ai o le maualuga o le IFITM1 faʻamatalaga i le kanesa colorectal tagata (CRC) e matua faʻatasi ma le CRC lymph node ma le mamao metastasis faʻapea foʻi ma se tulaga maualuga atu ile falemaʻi.O le mea taua, o le maualuga o le faʻaaliga IFITM1 o se faʻailoga tutoʻatasi mo le ola le lelei.Ina ia suʻesuʻeina le faʻaogaina o le mole, na matou faʻaalia ai le faʻaalia o le IFITM1 i sela CRC na faʻalauiloaina, ae o le tuʻituʻi o le faʻaaliga IFITM1 na faʻalavelaveina, femalagaiga / osofaʻiga ma le tumorigenicity in vitro.E le gata i lea, na matou faailoa mai le Caveolin-1 (CAV1) o se faʻataʻitaʻiga pito i lalo ole osofaʻiga a le IFITM1, ona o le tuʻituʻi o le CAV1 na faʻaumatia le siIFITM1 faʻasalalau le faʻalavelaveina o osofaʻiga i totonu o sela CRC.E le gata i lea, i totonu o le CRC cohort o 229 maʻi, o le faʻaaliga o le IFITM1 e faʻafeagai ma le faʻaaliga o le CAV1.O nei fa'ai'uga na fa'ailoa mai ai o le IFITM1 o lo'o fa'atupuina le malosi o le CRC sela, ma o se fa'ailoga fa'ata'ita'i ma fa'amoemoega fa'afoma'i mo le CRC.