Folic Acid Cas: 59-30-3 99%
| Numera Fa'amaumauga | XD90435 |
| Igoa Oloa | Folic Acid |
| CAS | 59-30-3 |
| Fuafua mole | C19H19N7O6 |
| Molecular Weight | 441.40 |
| Fa'amatalaga Teuina | Ambient |
| Fa'atonu Fa'asologa o Fa'asologa | 29362900 |
Fa'amatalaga o oloa
| Fa'aaliga | Samasama pe moli tioata pauta |
| Su'ega | 99% |
| Vai | 5.0 - 8.5% |
| Chromatographic mama | <2.0% |
| Solubility | Fa'ata'ita'i e le mafai ona fa'afefe i le vai ma le tele o so'o so'o.E fa'amavae i ni vai fa'afefete ma vaifofo alkaline |
| Toega i luga o le mumu | <0.3% |
I totonu o lenei suʻesuʻega, e faʻaogaina ai le poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-ploy(N-isopropylacrylamide-co-hydroxyethyl methacrylate) (FA-Pluronic-PNH) copolymer i lenei suʻesuʻega. tuufaatasia.O le fausaga ma le mamafa mole o le copolymer na faʻamaonia e le 1H NMR, FT-IR ma le GPC, i le faasologa.O le vevela vaifofo pito i lalo (LCST) o le copolymer o le 39.8 tikeri C. I le faʻaaogaina o le doxorubicin (DOX) e fai ma vailaʻau faʻataʻitaʻiga, na faʻapipiʻi atili ai le folate receptor-loaded micelles DOX-loaded i luga o le copolymer.O micelles avanoa ma DOX-loaded na faʻaalia uma foliga spherical ma o latou lautele lautele e 35 nm ma 50 nm, faasologa.O amioga fa'amalolo in vitro o micelles e uta DOX e fa'alagolago i le vevela ma o le fua o le fa'asa'olotoina o le DOX i le 42 tikeri C (i luga a'e o le LCST) sa vave atu nai lo le 37 tikeri C (lalo LCST).E le gata i lea, o su'esu'ega o le cytotoxicity ole fua ole DOX ma le DOX-loaded micelles i laina sela o le kanesa o le tino o le tagata HeLa ma laina sela o le kanesa o le mama o le tagata A549 na fa'aalia ai o le folate na fa'atuputeleina le fa'aogaina o le micelles i totonu o sela fa'atatau lea e tele naua fa'amatalaga folate receptors.
