Oloa

Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole] -7-Carboxylate o se vailaʻau vailaʻau o loʻo i ai faʻaoga faʻapitoa i vaega eseese, e aofia ai vailaʻau ma mea faʻasaienisi. pharmaceuticals, o lenei tuufaatasiga e mafai ona faʻaaogaina e fai ma amataga mo le atinaʻeina o vailaʻau fou.O le i ai o se fausaga autu o le benzimidazole faatasi ai ma vaega o le ethoxy ma le carboxylate e maua ai avanoa mo nisi suiga o vailaʻau e faʻaleleia ai ana mea tau vailaau.E mafai e foma'i vaila'au su'esu'e le fa'atulagaina-gaioiga sootaga (SAR) o lenei fa'apotopotoga e ala i le tu'ufa'atasia o ana analog ma fesuiaiga i filifili itu ma vaega fa'atino.E mafai ona fesoasoani lea i le fa'ailoaina o suiga fa'avae e fa'aleleia atili ai le malosi o vaila'au, filifili, ma mea tau pharmacokinetic. E fa'alautele atu fo'i le fa'aogaina o le fa'aogaina i le matata o meafaitino.O lona fausaga fa'alekemiki fa'apitoa ma vaega fa'atino e talafeagai mo le fa'aogaina o se poloka faufale i le tu'ufa'atasiga o mea fou.E mafai ona faʻaaogaina i le atinaʻeina o polymers, coatings, poʻo isi mea o loʻo i ai le faʻatulagaina saʻo o atoms ma le i ai o vaega faʻapitoa faʻapitoa e taua tele mo mea faʻaletino poʻo vailaʻau. 2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole] -7-Carboxylate e mafai ona avea o se su'esu'ega mole po'o se meafaigaluega i vaega eseese o su'esu'ega.O ona vaega fa'atino fa'apitoa e mafai ona fa'aoga talafeagai mo le fa'ailogaina po'o le fa'ailogaina o biomolecules patino mo fa'amoemoega fa'ata'ita'i.O lenei tuufaatasiga e mafai ona faʻaaogaina i suʻesuʻega faʻapitoa poʻo faʻataʻitaʻiga faʻataʻitaʻiga e suʻesuʻe ai fegalegaleaiga mole, fegalegaleaiga protein-protein, poʻo gaioiga feaveaʻi. E taua le matauina o le faʻaogaina o loʻo taʻua i luga e taumatemate, ma o le a faʻalagolago le faʻaoga moni i nisi suʻesuʻega ma iloiloga.O le a faia su'esu'ega fa'apitoa, e aofia ai su'ega in vitro ma in vivo, e su'esu'e ai ana gaioiga fa'aola, oona, ma isi mea tau vaila'au.E le gata i lea, o lona saogalemu ma le aoga o le a suʻesuʻeina maeʻaeʻa aʻo leʻi iloiloina lona faʻaogaina i falemaʻi. folafolaga i su'esu'ega vaila'au, fa'asaienisi meafaitino, ma le atina'eina o su'esu'ega mole.O lona fausaga faʻapitoa faʻapitoa e maua ai avanoa mo suiga, e mafai ai ona faʻamalosia le faʻaogaina o ana mea tau vailaau poʻo le faʻaogaina i le tuʻufaʻatasia o mea fou.Ae ui i lea, e manaʻomia nisi suʻesuʻega ma suʻega e suʻesuʻe ma faʻamaonia ana faʻaoga talafeagai i nei matāʻupu.