Oloa

Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride o se vailaʻau vailaʻau e maua ai le faʻaogaina i le matata o vailaʻau kemisi ma le atinaʻeina o vailaʻau.O lona fausaga mole e aofia ai se mama pyrrolidine ma se vaega tert-butyl i le tulaga cis, se vaega ethyl, ma vaega e lua carboxylate.O lenei tuufaatasiga e masani ona maua i foliga o se masima hydrochloride.O se tasi o faʻaoga autu o le cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride o loʻo i totonu o le tuʻufaʻatasia ma le atinaʻeina o vailaʻau faʻatatau i le ogatotonu. faiga neura (CNS).O le i ai o le mama pyrrolidine, faʻatasi ai ma le tert-butyl ma le ethyl vaega, e maua ai lenei faʻapipiʻi ma mea e mafai ona maua ai le neuroactive.E mafai e tagata suʻesuʻe ona faʻaogaina lenei faʻapipiʻi e fai ma mea amata e faʻapipiʻi ai analogs poʻo mea e maua mai e mafai ona filifili faʻatasi ma faʻamatalaga faʻapitoa poʻo enzymes i le CNS.E ala i le suia o le fausaga ma suitulaga, e mafai ona latou faʻamalieina le vailaʻau o le vailaʻau, faʻaleleia lona faʻafesoʻotaʻi, ma faʻaleleia lona malosi faʻapitoa. E le gata i lea, e mafai ona avea le cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride. fa'afaigaluegaina e avea o se meafaigaluega fa'apipi'i i su'esu'ega fa'aola e su'esu'e ai le sao o fa'ama'i fa'apitoa po'o enzymes i faiga fa'ailo.I le faʻaaogaina o lenei faʻapipiʻi e pei o se ligand poʻo se suʻesuʻega, e mafai e tagata suʻesuʻe ona suʻesuʻeina le fesoʻotaʻiga vavalalata, filifili, ma le faʻaogaina o gaioiga a nei talipupuni poʻo enzymes.O lenei faʻamatalaga e taua tele mo le malamalama i le faʻavae mole o faiga neuropharmacological ma mo le atinaʻeina o tala fou e faʻatatau i faʻafitauli o le neurodegenerative, faʻafitauli o le mafaufau, poʻo faʻamaʻi neurological.E mafai ona tu'ufa'atasia i totonu o faletusi o fa'aputuga, o lo'o fa'ata'ita'iina fa'asaga i fa'amoemoega eseese, e pei o talitali po'o enzymes, e fa'ailoa ai mea e mafai ona ta'ita'ia po'o sui o fualaau fa'asaina.O lenei suʻesuʻega e faʻatagaina ai le faʻamaoniaina o mea faʻapipiʻi e faʻaalia ai mea e manaʻomia mo vailaʻau poʻo ni aʻafiaga faʻapitoa e mafai.Prodrugs o mea fa'agata po'o fa'aleaogaina ua fa'atulagaina ina ia fa'agasolo i totonu o latou tino malosi i totonu o le tino.E ala i le suia o le fausaga o lenei tuufaatasiga, e mafai ai e tagata suʻesuʻe ona faia ni mea faʻapipiʻi e sili atu ona mautu, faʻaleleia le bioavailability, poʻo le mafai ona sopoia faʻaola meaola e sili atu ona faigofie.O lenei mea e mafai ona faʻaleleia atili ai le faʻaogaina o le vailaʻau ma faʻaleleia ana mea tau vailaau faʻamaʻi. , e avea o se meafaigaluega faʻapipiʻi mo suʻesuʻega o meaola, i le suʻeina o vailaʻau, ma i le atinaʻeina o vailaʻau.O lona fausaga mole mole tulaga ese e maua ai avanoa mo suiga ma le faʻaleleia atili e faʻaleleia ai ana mea tau vailaʻau ma gaioiga faʻaola.O le fegalegaleai ma le gafatia o lenei tuufaatasiga ua avea ai ma aseta taua i le tulaga o vailaau kemisi ma le atinaeina o fualaau faasaina.