Oloa

O le cystic fibrosis ose ma'i fa'aletagata lea e feso'ota'i ai le mucus fa'aletonu i totonu o mama ma le fa'ama'i pipisi.O le fa'ateteleina o le fa'ama'i o le fa'ama'i o le fa'ama'i ua sili atu ona ogaoga.O vailaʻau faʻamaʻi o se vaega taua o togafitiga mo faʻalavelave faʻafuaseʻi ma vailaʻau faʻamaʻi e mafai ona faʻaaogaina naʻo ia pe faʻatasi ma vailaʻau faʻamaʻi gutu mo faʻalavelave faʻafuaseʻi poʻo faʻamaʻi faʻamaʻi toto mo faʻamaʻi ogaoga.O vailaʻau faʻamaʻi inhaled e le mafua ai aʻafiaga leaga tutusa e pei o vailaʻau faʻamaʻi ma e mafai ona faʻamaonia se isi mea i tagata e le lelei le maua o latou veins.Ina ia iloa pe o le togafitiga o faʻalavelave faʻalavelave faʻafuaseʻi ma vailaʻau inhaled i tagata e maua i le cystic fibrosis e faʻaleleia ai le lelei o latou olaga, faʻaitiitia le taimi malolo. a'oga po'o galuega ma fa'aleleia atili lo latou ola umi.Sa matou su'esu'eina le ClinicalTrials.gov ma le Ofisa Resitala Fa'ata'ita'i Fa'afoma'i a Ausetalia ma Niu Sila mo su'ega talafeagai.Aso o le su'esu'ega mulimuli: 15 Mati 2012Sa matou su'eina fo'i le Cochrane Cystic Fibrosis G roup's Cystic Fibrosis Trials Register.Aso o le suʻesuʻega mulimuli: 01 Iuni 2012. Faʻataʻitaʻiga faʻapitoa faʻataʻitaʻiga i tagata e maua i le cystic fibrosis ma le faʻaleagaina o le pulmonary lea na faʻatusatusaina ai togafitiga faʻatasi ma vailaʻau faʻamaʻi i le placebo, togafitiga masani poʻo se isi vailaʻau faʻamaʻi mo le va o le tasi ma le fa vaiaso. filifilia faʻataʻitaʻiga agavaa, suʻesuʻeina le lamatiaga o le faʻaituau i faʻataʻitaʻiga taʻitasi ma maua mai faʻamaumauga.Na faʻafesoʻotaʻi tusitala o faʻataʻitaʻiga na aofia ai mo nisi faʻamatalaga. E ono faʻataʻitaʻiga ma 208 tagata auai na aofia i le iloiloga.O faʻataʻitaʻiga e eseese i mamanu ma faʻalavelave (peitaʻi, o faʻataʻitaʻiga uma e aofia ai faʻataʻitaʻiga faʻatusatusa ile inhaled versus intravenous antibiotic regimens).A'afiaga o le fa'aituau sa faigata ona iloilo i le tele o su'ega.E le'i lipotia atoatoa i'uga ma na'o fa'amaumauga fa'atapula'a na maua mo su'esu'ega.E fa suʻesuʻega na lipotia ai nisi o faʻaiʻuga i luga o le faʻamalosia o le manava i le tasi sekone ma maua ai le leai o se eseesega tele i le va o vailaʻau faʻamaʻi ma le faʻatusatusaina o tama.I le lua o nei faʻataʻitaʻiga e faʻaaoga ai le 300 mg o le inhaled tobramycin, o le suiga i le faʻamalosia o le manava faʻamalosi i le tasi sekone e tutusa ma le tobramycin intravenous;ma i le tasi faamasinoga o le taimi seia oo i le isi faateteleina e le ese.E leai ni a'afiaga taua na lipotia. E itiiti ni fa'amaoniga maualuga aoga e fa'amasinoina ai le aoga o vaila'au fa'ama'i mo le togafitia o fa'alavelave fa'alavelave i tagata e maua i le cystic fibrosis.O fa'ata'ita'iga na aofia ai e le'i lava le malosi e ausia ai a latou sini.O le mea lea, e le mafai ona tatou faʻaalia pe sili atu le tasi togafitiga nai lo le isi pe leai.E mana'omia nisi su'esu'ega e fa'amautu ai pe mafai ona fa'aogaina le tobramycin inhaled e fai ma sui i le tobramycin tui mo nisi fa'alavelave mamafa.