Oloa

Benzyl N-[2-(piperidin-4-yl) propan-2-yl]carbamate hydrochloride o se vailaʻau faʻasaina e masani ona faʻaaogaina i suʻesuʻega vailaʻau ma le atinaʻeina o vailaʻau.O lona fausaga mole e aofia ai se vaega benzyl faʻapipiʻi i se vaega galue carbamate e ala i le piperidine moiety.O se tasi o faʻaoga muamua o Benzyl N-[2-(piperidin-4-yl) propan-2-yl]carbamate hydrochloride o se mea muamua. po'o le vaeluagalemu i le tu'ufa'atasiga o vaila'au eseese.O le i ai o le piperidine mama e maua ai le faʻaogaina o lenei mea i le faʻaogaina o kemisi kemisi, ma avea ai ma mea aoga amata mo le faʻapipiʻiina o molelaʻau lavelave eseese.E ala i le tuʻuina atu o lenei mea faʻapipiʻi i totonu o se auala faʻapipiʻi, e mafai e kemisi ona faʻaogaina le tele o mea faʻapipiʻi fou e mafai ona faʻaogaina togafitiga. se poloka faufale mo le atinaʻeina o vailaʻau fou e faʻatatau i ala faʻapitoa poʻo ni tali.O ona foliga fa'atulagaina e talafeagai ai mo le tu'ufa'atasia i molela'au vaila'au, e fai o se pharmacophore po'o se vaega fa'atino autu e nafa ma le gaioiga mana'omia.E ala i le suia o le benzyl, piperidine, poʻo le carbamate vaega, e mafai e tagata suʻesuʻe ona faʻamaonia le malosi o le vailaʻau, filifiliga, ma mea tau vailaʻau. E mafai foi ona avea le faʻapipiʻi o se mea faigaluega poʻo se faʻamatalaga faʻamatalaga mo suʻesuʻega vailaʻau ma suʻesuʻega faʻatulagaina-gaioiga (SAR).E ala i le faʻatusatusaina o gaioiga faʻaola o mea eseese poʻo analogs o Benzyl N-[2-(piperidin-4-yl) propan-2-yl]carbamate hydrochloride, e mafai e tagata suʻesuʻe ona maua faʻamatalaga i le fausaga-gaioiga sootaga, faʻatagaina i latou e mamanuina sili atu le malosi. ma fa'apotopotoga filifilia.O lenei faʻamatalaga e taua tele mo le faʻaleleia atili o le taʻitaʻia o le taʻitaʻia ma le atinaʻeina o sui o vailaʻau e sili atu ona aoga. e suʻesuʻe le faiga o gaioiga a nisi vailaʻau poʻo le suʻesuʻeina o le metabolism o fualaau.E ala i le fa'aogaina o fa'ailoga ua fa'aigoaina pe fa'ailogaina o lenei fa'apotopotoga, e mafai ai e tagata su'esu'e ona siaki lona tufatufaina ma le metabolism i faiga fa'aola.O nei faʻamatalaga e fesoasoani i le malamalama pe faʻafefea ona faʻaogaina fualaau ma faʻamalo i totonu o le tino, tuʻuina atu faʻamatalaga taua i fegalegaleaiga faʻatau fualaau, faʻasologa o vailaʻau, ma faʻalavelave faʻalavelave faʻasaina. I le aotelega, Benzyl N-[2-(piperidin-4-yl)propan- 2-yl]carbamate hydrochloride ose fa'aputuga tele fa'aoga tele i su'esu'ega vaila'au ma le atina'eina o vaila'au.O ona foliga faʻatulagaina e taua tele e avea o se mea muamua mo le tuʻufaʻatasia o vailaʻau vailaʻau eseese ma o se poloka fale mo le atinaʻeina o vailaʻau fou.E le gata i lea, e avea o se meafaigaluega mo suʻesuʻega SAR, suʻesuʻega o vailaʻau, ma suʻesuʻega metabolism.O faʻaoga eseese o le Benzyl N-[2-(piperidin-4-yl) propan-2-yl]carbamate hydrochloride o loʻo faʻamaonia ai lona taua i le atinaʻeina o vailaʻau fou ma le alualu i luma o vailaʻau kemisi.