Oloa

5,6-Dihydro-3-(4-morpholinyl) -1-[4-(2-oxo-1-piperidinyl)phenyl] -2(1H) -pyridinone, e taʻua foi o le DPHP, o se heterocyclic compound ma faʻaoga eseese. i vaila'au kemisi ma su'esu'ega vaila'au.O se faʻamatalaga lenei o lona faʻaogaina i le tusa ma le 300 upu. DPHP e lauiloa mo lona gafatia e avea o se inhibitor malosi ma filifili o nisi enzymes ma tali i le tino o le tagata.O se tasi o ana faʻaoga muamua o loʻo i totonu o le fanua o le kinase inhibition.Kinases o enzymes e tele sona sao i le cell signaling path ma e masani ona aʻafia i faʻamaʻi eseese, e aofia ai le kanesa.O le DPHP ua maua e filifili faʻalavelave faʻapitoa kinases, ma faʻalavelaveina ai faʻailoga faʻailoga aberrant e fesoasoani i le alualu i luma o faʻamaʻi.O le mea lea ua avea ai ma sui tauva mo le atinaʻeina o togafitiga faʻatatau mo le tele o faʻamaʻi, e aofia ai le kanesa, mumū, ma faʻafitauli o le neurological. E le gata i lea, ua faʻaalia e le DPHP le gafatia i le vaega o le anti-inflammatory and immunomodulatory activity.O le fulafula o se tali masani a le tino i faʻamaʻi poʻo manuʻa ae e mafai ona faʻasolosolo ma oʻo atu ai i faʻamaʻi eseese.Ua faʻaalia e le DPHP le malosi e faʻalavelaveina ai nisi o auala faʻapitoa, faʻaitiitia le gaosiga o faʻasalalauga faʻafefe.O lenei meatotino e avea ma meafaigaluega taua i le atinaʻeina o vailaʻau faʻamaʻi, fesoasoani i le togafitiga o tulaga e pei o le rumatika, faʻamaʻi faʻamaʻi, ma le foma. DPHP ua suʻesuʻeina foi mo lona gafatia e avea o se faʻamaʻi poʻo se faʻamaʻi tiga. .O le tiga fa'atiga ose fa'afitauli fa'alesoifua maloloina, ma o togafitiga o lo'o i ai nei e masani ona i ai ni tapula'a po'o ni a'afiaga e le mana'omia.Ua fa'aalia e le DPHP a'afiaga fa'ama'i i su'esu'ega fa'apitoa, e fa'ailoa mai ai lona gafatia e avea o se tala fa'afoma'i mo le puleaina o tiga.E ala i le faʻavasegaina o faʻamatalaga faʻapitoa ma neurotransmitters e aʻafia i lagona tiga, e mafai e le DPHP ona ofoina atu se isi auala i le puleaina o tiga ma e ono faʻaitiitia ai aʻafiaga.O tulaga fa'aletino e pei ole fa'ama'i o le Alzheimer ma le fa'ama'i o Parkinson e a'afia ai faiga fa'alavelave ma le fa'asa'olotoina o fa'ama'i ma enzymes i le fai'ai.DPHP ua suʻesuʻeina mo lona gafatia e avea o se neuroprotective agent ma mo lona gafatia e faʻaleleia ai le gaioiga o le mafaufau.E ala i le tulimataʻiina o faʻasalalauga faʻapitoa ma auala e aʻafia ai i faʻafitauli o le neurodegenerative, DPHP o loʻo umia le folafolaga e avea o se togafitiga faʻapitoa mo nei tulaga luʻitau. 1-piperidinyl) phenyl] -2 (1H) -pyridinone (DPHP) o se faʻalapotopotoga faʻapitoa ma faʻaogaina faʻaoga i le kinase inhibition, anti-inflammatory activity, analgesia, ma le neuroprotection.O lona gafatia e filifili fa'avasega fa'ainisinia ma fa'ama'i o lo'o a'afia i ala fa'ama'i ua avea ai ma sui aulelei mo su'esu'ega vaila'au ma togafiti fa'afoma'i.O isi su'esu'ega ma atina'e e mafai ona fa'aalia ai fa'aoga fa'aopoopo ma fa'asilisili ona meatotino mo fa'ailoga fa'apitoa.