Oloa

5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine o se vailaʻau faʻamaʻi e maua ai le aoga i suʻesuʻega eseese, vailaʻau, ma fale gaosi oloa.O lenei tuufaatasiga ua lauiloa mo lona natura tele ma le gafatia o loʻo umia mo le atinaʻeina o molelaʻau tulaga ese ma vailaʻau ona o lona fausaga faʻapitoa ma vaega faʻafefe. fualaau faasaina.O le iai o le bromine atom, fluorine atom, isopropyl group, ma le pyrimidine ring structure ua avea ai ma poloka fale matagofie mo le fatuina o molelaʻau fou ma mea e manaʻomia.E mafai e fomaʻi ma suʻesuʻega faʻafomaʻi ona faʻaleleia ma faʻaogaina lenei mea faʻapipiʻi e faʻaalia ai galuega faʻapitoa poʻo foliga faʻavae e aoga mo le faʻaogaina o vailaʻau faʻasaina poʻo le faʻaleleia atili o le pharmacokinetic.O le vaega methylsulfonyl e mafai ona feagai ma faʻalavelave eseese, e pei o le nucleophilic displacement, elimination, poʻo le faʻamaʻiina, faʻatagaina mo le faʻaofiina o vaega galue eseese i totonu o le mole mole.O lenei felagolagoma'i e taua tele mo le fa'atupuina o mea fa'aola lavelave i totonu o le falesu'esu'e.O le fluorine atom ma isi mea e suitulaga e mafai ona saofagā i le fa'aogaina o mea fa'apitoa fa'aletino po'o vaila'au, ma fa'amalieina ai mo le su'esu'eina o fa'alavelave fa'apitoa po'o le fa'aogaina fo'i mo su'esu'ega fa'atusatusa.E masani ona faʻaaogaina e le au suʻesuʻe ia mea faʻapipiʻi e malamalama ai i fegalegaleaiga faʻaola, suʻesuʻega faʻasologa o gaioiga, atiaʻe auala fou faʻapipiʻi, poʻo le faʻaleleia o le faʻatinoga o faiga faʻapisinisi o loʻo iai. 4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine e mafai ona fesuisuiaʻi e faʻatatau i le vaega patino o suʻesuʻega poʻo alamanuia.O le faʻaogaina o le faʻaogaina e faʻalautele atu i tua atu o mea na taʻua muamua, ma o lona aoga e mafai ona suʻesuʻeina e chemists, pharmacologists, biochemists, ma isi saienitisi o loʻo aʻafia i suʻesuʻega vailaʻau, mea faasaienisi, poʻo suʻesuʻega mole. I le aotelega, 5-(Bromomethyl) -4 - (4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine o se faʻalapotopotoga faʻapitoa e umia folafolaga i vailaʻau, vailaʻau, ma suʻesuʻega faʻapisinisi.O lona fausaga fa'apitoa ma vaega fa'agaoioiga ua avea ai ma poloka fau fau mo le tu'ufa'atasia o molela'au vaila'au fou ma su'esu'ega fa'a'ese'esega fa'a-kemikolo.O le fa'aogaina o le fa'aogaina e lautele, ma o le su'esu'eina atili o ona meatotino e mafai ona maua ai le ala mo le alualu i luma i le tele o matata fa'asaienisi.