Oloa

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl, lea e taʻua foi o le FIMPA, o se vailaʻau vailaʻau ma se fausaga lavelave e iai le malosi. talosaga i su'esu'ega tau vailaau ma le atina'eina o fualaau.O loʻo faʻavasegaina o se pyrimidine faʻatasi ma se vaega formyl o loʻo faʻapipiʻi i le 5th carbon atom, ma se 4-fluorophenyl ma se isopropyl vaega faʻapipiʻi i le 4th ma le 6th carbon atoms, taʻitasi. O se tasi o talosaga taua a le FIMPA o loʻo i le fanua su'esu'ega o le kanesa.Pyrimidine derivatives ua suʻesuʻeina tele mo a latou meatotino antitumor, ma o loʻo faʻaalia e le FIMPA le gafatia e avea o se vailaʻau faʻamaʻi.O ona foliga fa'atulagaina ua avea ai ma sui tauva mo le fa'alavelaveina o enzymes autu po'o ni tali e a'afia i le tuputupu a'e ma le alualu i luma.E mafai e tagata suʻesuʻe ona toe faʻaleleia atili le fausaga o le FIMPA e faʻaleleia atili ai lona malosi, filifilia, ma mea tau vailaau mo togafitiga sili atu ona lelei o le kanesa.O lona fausaga tulaga ese e mafai ai ona faʻapipiʻi vaega eseese o galuega, lea e mafai ona faia se sao taua i le fegalegaleai ma sini mole mole.O lenei agavaʻa e avea ai le FIMPA ma meafaigaluega taua i vailaʻau kemisi mo le atinaʻeina o vailaʻau faʻafomaʻi fou e faasaga i faʻamaʻi eseese e pei o faʻamaʻi o le neura poʻo faʻamaʻi pipisi.O ona vaega fa'atino fa'agaioiga, e pei o le formyl ma le sulfonyl group, e mafai ona avea ma nofoaga mo nisi suiga fa'a-kemikolo.E mafai e tagata suʻesuʻe ona faʻaogaina le FIMPA e fai ma mea amata poʻo se mea faʻapipiʻi e maua ai mea e maua mai ai, e mafai ona suʻeina mo a latou gaioiga faʻaola pe faʻaaogaina e fai ma poloka fale mo le faʻapipiʻiina o molelaʻau sili atu ona faigata. I le aotelega, 4- (4-Fluorophenyl) -6-Isopropyl -2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl (FIMPA) o loʻo faʻaalia ai le gafatia i vaega eseese o suʻesuʻega vailaʻau ma le atinaʻeina o vailaʻau.O lona fausaga tulaga ese ma vaega galue e avea ma meafaigaluega taua mo le mamanuina o sui fou o fualaau faasaina poʻo le faʻapipiʻiina o mea faʻapipiʻi lavelave.O le su'esu'eina atili ma le fa'asilisiliina o mea totino a le FIMPA e mafai ona ta'ita'iina ai le mauaina o ni vaila'au fa'afoma'i fou ma saofagā i le aga'i i luma i le matata o vaila'au kemisi.