Oloa

Ina ia suʻesuʻeina le aoga aoga o le tuʻufaʻatasia o le butyrate, Lactobacillus casei, ma le L-carnitine i se faʻataʻitaʻiga rat colitis. Na vaevaeina iole i vaega e fitu.E fa vaega na maua le oral butyrate, L-carnitine, Lactobacillus casei ma le tuʻufaʻatasia o sui e tolu mo le 10 aso sosoo.O vaega na totoe na aofia ai pulega le lelei ma le lelei ma se vaega taufaasese.Macroscopic, su'esu'ega histopathological, ma biomarkers e pei ole tumor necrosis factor-alpha (TNF-α) ma interlukin-1β (IL-1β), myeloperoxidase (MPO), thiobarbituric acid reactive substances (TBARS), ma le fa'aitiitia o le malosi ole plasma (FRAP). ) na faʻamoemoeina i totonu o le kolone. O le tuʻufaʻatasiga togafitiga na faʻaalia ai se aoga aoga tele i le faʻaitiitia o le colitis pe a faʻatusatusa i faʻatonuga.O suiga atoa i le faʻaitiitia o le TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / mg protein, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg / mg protein, P <0.05). ± 0.03 vs 0.49 ± 0.04 μg/mg porotini, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg protein, P <0.05), ma le maualuga o le FRAP (23.46 ± 1.02 μL vs 1.02 μL). , P <0.05) lagolago le manaʻoga o le tuʻufaʻatasiga togafitiga pe a faʻatusatusa i faʻatonuga.E ui lava o le monotherapies sa aoga foi i le faʻaleleia o faʻailoga colitis, o le togafitiga tuʻufaʻatasia na sili atu ona lelei i le faʻaleleia o faʻamaʻi faʻamaʻi faʻamaʻi faʻamaʻi e aofia ai le FRAP, TBARS, ma le MPO. le fa'atulagaina o falema'i.