Oloa

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) o se vailaʻau faʻamaʻi ua lauiloa mo ana faʻaoga i le faʻaogaina o meaola, aemaise lava i le fanua o kemisi carbohydrate.O se mea e maua mai i le D-glucose, o se suka e tupu mai i le natura, ma o loʻo i ai ni mea faʻapitoa e faʻaaogaina ai le tele o gaioiga faʻamaʻi.Carbohydrates, e aofia ai suka, e mafai ona tele vaega hydroxyl, e mafai ona tali atu i isi reagents pe oʻo i suiga e le manaʻomia i le taimi o le faʻasologa.E ala i le puipuia o vaega fa'apitoa ole hydroxyl e fa'aaoga ai le TMS-D-glucose lactone, e mafai e foma'i vaila'au ona fa'atonutonu taunu'uga o tali ma fa'aogaina lelei le fa'atulagaina o ga'o.A maeʻa gaioiga manaʻomia, e mafai ona faigofie ona aveese vaega puipuia, faʻaalia le oloa manaʻomia.TMS-D-glucose lactone e maua ai foʻi talosaga e avea o se vaeluagalemu i le tuʻufaʻatasia o mea e sili atu ona lavelave carbohydrate derivatives.E ala i le fa'avasegaina o vaega o le hydroxyl o le TMS-D-glucose lactone, e mafai e kemisi ona fa'aofia le tele o vaega fa'atino po'o isi mea e suitulaga i totonu o le mole mole ga'o.O lenei mea e mafai ai mo le fausiaina o mea faʻapipiʻi faʻavae gaʻo eseese e mafai ona faʻaogaina i vailaʻau, mea teuteu, ma mea faʻasaienisi.Glycosylation o se laasaga autu i le fausiaina o fusi glycosidic, lea e taua mo le fausiaina o gaʻo ma glycoconjugates.O le TMS-D-glucose lactone e mafai ona liua i glycosyl donors, lea e galue e pei o ni mea faʻafesoʻotaʻi i gaioiga glycosylation, e mafai ai ona faʻapipiʻi gaʻo i isi mole.E ala i le tu'uina atu o le TMS-D-glucose lactone i le polymerization reactions, e mafai e foma'i kemisi ona faia ni filifili polymer po'o feso'ota'iga ma ponaivi ga'o.O nei polymers carbohydrate e mafai ona i ai ni mea faʻapitoa ma e mafai ona maua ni faʻaoga i vaega e pei o le tuʻuina atu o vailaʻau, bioengineering, ma biomaterials.E taua le matauina o le TMS-D-glucose lactone e tatau ona taulimaina ma le faʻaeteete ona o lona susu ma le ea.E masani ona teuina ma taulimaina i lalo o le nitrogen poʻo le argon atmospera e puipuia ai le faʻaleagaina. I le aotelega, 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) o se faʻalapotopotoga faʻapitoa e faʻaaogaina lautele i totonu. kemisi carbohydrate.O ana fa'aoga autu e aofia ai le puipuia o kemisi vaega, fa'asologa o le vaeluagalemu, fa'avaeina o foa'i glycosyl, ma le gaosiga o polymers fa'avae carbohydrate.E ala i le fa'aaogaina o le TMS-D-glucose lactone i nei fa'agasologa, e mafai ai e foma'i kemisi ona maua lelei le fa'atonutonuina o ga'o ga'o ma fa'atupu mea 'ese'ese ga'o ga'o ma fa'aoga talafeagai i matā'upu 'ese'ese.