Oloa

1-Methyl-4-pyrazole boronic acid pinacol ester o se faʻapipiʻi faʻatasi ma le tele o faʻaoga, aemaise lava i le fanua o le faʻaogaina o meaola.O lona fausaga tulaga ese ma le gaoioi e taua tele i gaioiga eseese o vailaʻau ma o se poloka fale mo le tuʻufaʻatasia o molelaʻau lavelave.O se tasi o faʻaoga autu o le 1-Methyl-4-pyrazole boronic acid pinacol ester o loʻo i le fausiaina o carbon-carbon poʻo fusiga kaponi-heteroatom.O le vaega o le boronic acid i totonu o le mole e mafai ona feagai ma Suzuki-Miyaura cross-coupling reactions, e mafai ai ona faʻapipiʻi le 1-methyl-4-pyrazole moiety i isi faʻalapotopotoga poʻo vaega galue.O lenei tali e mafai ai e chemists ona faia ni mea faʻapipiʻi lavelave faʻatasi ma fausaga faʻapitoa ma meatotino. E le gata i lea, o le pinacol ester group i totonu o le mole e maua ai le mautu ma puipuia le gaioiga o le boronic acid i taimi o gaioiga eseese.O lenei vaega puipuia e mafai ona faigofie ona aveese i lalo o tulaga malu, ma faʻaalia ai le vaega o le boronic acid mo nisi suiga.O le mea lea, o le 1-Methyl-4-pyrazole boronic acid pinacol ester e avea o se vaeluagalemu i le tuʻufaʻatasia o vailaʻau, agrochemicals, ma isi vailaʻau lelei. sui tauva fualaau faasaina.I le faʻaaogaina o le 1-Methyl-4-pyrazole boronic acid pinacol ester e fai ma mea amata, e mafai e kemisi ona faʻafeiloaʻi le 1-methyl-4-pyrazole moiety i totonu o se mole mole, tuʻuina atu faʻapitoa poʻo galuega.O mea fa'atupu e mafai ona fa'aalia ai le fa'aleleia atili o gaioioiga, fa'aleleia atili o vaila'au, po'o le fa'aitiitia o le oona. E le gata i lea, o le 1-Methyl-4-pyrazole boronic acid pinacol ester e taua i meafaitino faasaienisi ma catalysis.E mafai ona avea o se ligand, faʻamaopoopoina ma faʻamaʻi uʻamea ma auai i gaioiga eseese catalytic.Ole vaega ole vaila'au boronic e mafai ona fa'atupu fa'alavelave fa'atasi ma u'amea suiga, e fa'atagaina ai le fa'agaoioia o noataga CH po'o le fa'ata'atiaga o tali fa'alava.O nei meatotino e aoga mo le tuʻufaʻatasia o mea faigaluega poʻo le atinaʻeina o faiga fou catalytic. I le aotelega, 1-Methyl-4-pyrazole boronic acid pinacol ester o se faʻalapotopotoga faʻapitoa ma faʻaoga taua i le faʻaogaina o meaola, vailaʻau, mea faasaienisi, ma fa'atosina.O lona fa'aogaina o le boronic acid ma le pinacol ester group e fa'aogaina ai le gaogao-carbon po'o le carbon-heteroatom bond formation reactions, e mafai ai ona fausia ni mole lavelave.O ana fa'aoga e fa'alautele ai pisinisi eseese, e aofia ai le tu'ufa'atasiga o vaila'au, atina'e o mea faigaluega, ma le fa'alauteleina o faiga fa'agata.O le agavaʻa ma le faʻaogaina o le 1-Methyl-4-pyrazole boronic acid pinacol ester ua avea ma meafaigaluega taua mo kemisi o loʻo galulue i le faʻapipiʻiina o mea fou ma le mamanu o fofo fou.