Oloa

1-(3-Carboxypyrid-2-yl) -2-phenyl-4-methyl-piperazine, e taʻua foi o le CPPMP, o se vailaʻau vailaʻau faʻatasi ai ma se fausaga faʻalavelave o loʻo i ai le tele o faʻaoga faʻaoga i le matata o vailaʻau kemisi. o le CPPMP o loʻo i le togafitiga o faʻafitauli o le neura.O le i ai o se vaega o le carboxypyridyl e faʻaalia ai lona gafatia e fegalegaleai ma faʻamatalaga faʻapitoa neuronal i totonu o le fatugalemu o le tino.O le tulituliloaina o nei talipupuni e mafai ona faʻaogaina le neurotransmission, e ono taʻitaʻia ai togafitiga faʻapitoa i tulaga e pei o le atuatuvale, popole, poʻo le neurodegenerative disorders.O isi suʻesuʻega e manaʻomia e suʻesuʻe ai fesoʻotaʻiga faʻapitoa ma le faʻaogaina o le CPPMP ina ia mafai ai ona faʻamalosia lona gafatia e avea o se vailaʻau faʻamaʻi mo faʻafitauli o le neura.E mafai e foma'i vaila'au ona suia vaega 'ese'ese o lona fausaga e fa'aleleia atili ai ana mea fa'afoma'i po'o le fa'atatau i ala fa'apitoa.E ala i le faʻaleleia atili o le fausaga o le CPPMP, e mafai e le au suʻesuʻe ona mamanuina mea e maua mai i le faʻaleleia atili o le filifilia, malosi, ma faʻamatalaga saogalemu, ma avea ai i latou ma sui talafeagai mo vailaʻau e faʻatatau i faʻamaʻi eseese. pa'u o le sela ma le avanoa i totonu o le toto.O lenei vaega e mafai ona faʻaaogaina e mamanu ai vailaʻau fou e faʻatatau tonu i totonu ole intracellular enzymes poʻo auala, e maua ai avanoa mo togafitiga faʻamaʻi i faʻamaʻi e pei o le kanesa poʻo faʻafitauli faʻaleagaina. .E ala i le suia o lona vaega carboxypyridyl, e mafai ona mamanuina le tuufaatasiga ina ia sili atu ona mautu pe itiiti oona i lona tulaga moni, aʻo lelei le tuʻuina atu o vailaʻau malosi i le nofoaga o loʻo manaʻomia.O ia suiga e mafai ona faʻaleleia atili ai le bioavailability ma togafitiga faʻapitoa o le faʻaogaina.E le gata i lea, o le faʻaaogaina uma o le CPPMP e manaʻomia le mulimulitaʻia o faʻamaumauga saogalemu ma taʻiala e faʻamautinoa ai le taulimaina lelei ma faʻaitiitia ai le lamatiaga. , o lo'o i ai folafolaga mo fa'aoga eseese i kemisi fa'afoma'i.O lona fausaga faʻalavelave e maua ai avanoa mo le atinaʻeina o vailaʻau faʻafomaʻi fou mo faʻafitauli o le neurological, faʻapea foʻi ma vailaʻau e faʻatatau i faʻamaʻi eseese.Faatasi ai ma nisi suʻesuʻega ma faʻataʻitaʻiga, e mafai e le CPPMP ona faia ni sao taua i le matata o vailaʻau ma faʻaleleia taunuuga o maʻi.